Familial Alzheimer disease Presenilin-1 mutations alter the active site conformation of γ-secretase September 3, 2014 by De Ming Chau Comments are off Posted in:De Ming Chau See more Prev:A novel high-throughput 1536-well Notch1 γ-secretase AlphaLISA assay. Back: All Publications Next:Development of clickable active site-directed photoaffinity probes for γ-secretase