Development of clickable active site-directed photoaffinity probes for γ-secretase September 3, 2014 by De Ming Chau Comments are off Posted in:De Ming Chau See more Prev:Familial Alzheimer disease Presenilin-1 mutations alter the active site conformation of γ-secretase Back: All Publications Next:Piperidine acetic acid based γ-secretase modulators directly bind to presenilin-1.